김민혜

PARP-1 activation prevents OA pathogenesis by inhibiting apoptosis in chondrocytes

This study demonstrates that PARP-1 plays a protective role in preserving cartilage integrity under OA conditions. Its deficiency leads to increased apoptosis and cartilage egeneration both in vivo and in vitro. These findings highlight the regulatory role of PARP-1 in OA athogenesis and underscore the need for further investigation into its underlying mechanisms.

2026-02-27